During The Synthesis Of Atp, What Is The Direction Of Hydrogen Flow?, A. From Matrix To Intermembrane Space, B. From Intermembrane Space To Matrix, C
"During the synthesis of ATP, what is the direction of hydrogen flow?
a. from matrix to intermembrane space
b. from intermembrane space to matrix
c. from matrix of mitochondrion to cytoplasm
from cytoplasm to matrix of mitochondrion
"
Answer:
a. from the matrix to intermembrane space
The net result is the pumping of H+ across the inner membrane, from the matrix to the intermembrane space, driven by the energetically favorable flow of electrons.
Explanation:
This movement of H+ has two major consequences:
1. It has generated a pH gradient across the inner mitochondrial membrane, with the pH higher in the matrix than in the cytosol, where the pH is generally close to 7. (Since small molecules equilibrate freely across the outer membrane of the mitochondrion, the pH in the intermembrane space is the same as in the cytosol.)
2. It has generated a voltage gradient (membrane potential) across the inner mitochondrial membrane, with the inside negative and the outside positive (as a result of the net outflow of positive ions).
The pH gradient (ΔpH) drives H+ back into the matrix and OH- out of the matrix, thereby reinforcing the effect of the membrane potential (ΔV), which acts to attract any positive ion into the matrix and to push any negative ion out.
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CODE: 9.22.1.4.
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